Studies on Medicinal Chemistry Potentials of Hannoa undulata Essential Oil

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Anayo Joseph Uraku
Oluchi Helen Uraku
Onyema Simon Azi
Lilian Nwanneka Ebenyi
Victor Ugadu-Omoha Nwankwo
Bashiru Mohamed Koroma


Background: Hannoa undulata is a woody tree and shrub that belong to the family of Simaroubaceae. It is a perennial plant distributed in tropical and subtropical region of Africa. The plant is known for its medicinal value and the potency according to tradomedicine practitioners is very tremendous. The plant is acclaimed to be use in treatment of verse array of ailments viz: cancer, leprosy, tuberculosis, insanity, dementia, viral infection and prevention of abscesses in children among others. Due to the
acclaimed therapeutic uses of the plant, this study was aimed at determining the possible bioactive components of leaves and barks of H. undulata using GC-MS analysis.

Methods: The fresh leaves and bark stems of H. undulata were obtained from the plant and shade dried at room temperature. The dried leaves and bark stems were minced into fine powder. The bioactive combinations were done by GC-MS.

Results: The mass spectrum of the compounds found in the essential oils were matched with the National Institute of Standards and Technology (NIST) library Nine and twenty one phytocompounds were identified in the methanol leaf and bark stem extracts of the plant respectively. The major chemical constituents of the leaf include; 3,3-dimethoxyprop-1-en-1-ylium (4.77%), 5-methyl-1,3-oxazolidin-2-one (6.23%), furan-2-carboxylic acid (8.16%), ethyl palmitate (8.89%), 9,12,15-octadecatrien-1-ol (12.44%), hexadecanoic acid (17.86%), 7, 10,13-octadecatrien-1-ol (36.89%) while that of the bark are hexadec-14-en-1-ylium (6.69%), oleic acid (9-octadecenoic acid) (8.17%), hexadec-15-en-1-ylium (9.12%), di-n-octyl phthalate (16.14%), 3-(hydroxy {2-[(2-methylpropoxy) carbonyl] phenyl} methoxy)-2-methylprop-1-ylium (16.51%).

Conclusion: The presence of these compounds in the plant extract may be conscientious for the pharmacological properties of H. undulata and thus recommended as plant of phytopharmaceutical importance.

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How to Cite
Uraku, A. J. ., Uraku, O. H. ., Azi, O. S. ., Ebenyi, L. N. ., Nwankwo, V. U.-O. ., & Koroma, B. M. . (2022). Studies on Medicinal Chemistry Potentials of Hannoa undulata Essential Oil: The Nigerian Journal of Pharmacy, 56(2). Retrieved from
Author Biography

Anayo Joseph Uraku, Department of Biochemistry, Ebonyi State University, Abakaliki, Nigeria.

Department of Biological Sciences, Njala University, Freetown, Sierra Leone.


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